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Back to: Our Providers / biotez / Recombinant Human ADAMTS1, truncated, His-tagged (Recombinant Protein)
Size
5 µg/ 25 µl
Price
149.00
Catalog
30 400 402
Quick and safe buy process
Peptide sequence
F V S S H R Y V E T M L V A D Q S M A E F H G S G L K H Y L L T L F S V A A R L Y K H P S I R N S V S L V V V K I L V I H D E Q K G P E V T S N A A L T L R N F C N W Q K Q H N P P S D R D A E H Y D T A I L F T R Q D L C G S Q T C D T L G M A D V G T V C D P S R S C S V I E D D G L Q A A F T T A H E L G H V F N M P H D D A K Q C A S L N G V N Q D S H M M A S M L S N L D H S Q P W S P C S A Y M I T S F L D N G H G E C L M D K P H N P I Q L P G D L P G T S Y D A N R Q C Q F T F G E D S K H C P D A A S T C S T L W C T G T S G G V L V C Q T K H F P W A D G T S C G E G K W C I N G K C V N K T D R K H F D T P F H G N W G M W G P W G D C S R T C G G G V Q Y T M R E C D N P V P K N G G K Y C E G K R V R Y R S C N L E D C P D N (H)6
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Protein description
ADAMTS1 cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover (By similarity). Has angiogenic inhibitor activity. Active metalloprotease, which may be associated with various inflammatory processes as well as development of cancer cachexia. May play a critical role in follicular rupture.
Research area interests
Diseases associated with ADAMTS1 include Type 2A Von Willebrand Disease and Mongolian Spot. Among its related pathways are Diseases associated with O-glycosylation of proteins and Transport to the Golgi and subsequent modification.
Other names
A Disintegrin-Like And Metalloprotease (Reprolysin Type) With Thrombospondin Type 1 Motif, 1; Human Metalloproteinase With Thrombospondin Type 1 Motifs
Tested applications
Degradation of extracellular matrix proteoglycans; screening and characterization of inhibitors; Standard in enzymatic and immunological assays
Other desciption
Recombinant human ADAMTS1 Δ618-968 is produced with the baculovirus expression system and purified from insect cell culture supernatants.
Protein family
ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family.
Contents
50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 5 mM CaCl2, 0.05 % Brij-35 Detergent.
Full name
ADAM metallopeptidase with thrombospondin type 1 motif 1 (partial)
Technical datasheet
Contact us to receive the datasheet
Source
Recombinants or rec. proteins
Purification
Mentioned in the data sheet
Warnings
For Research Use only.
PubMed citations
See the data sheet
Abbreviation
ADAMTS1 (partial)
Product Subtype
protein fragment
Storage condition
Store at -70°C
Protein subtype
EC 3.4.24.82
Group
recombinants
Protein type
Recombinant
Expression system
Insect Cell
Tag
His-tagged
Conjugation
histidine
Shipping conditions
dry ice
UniProt number
Q9UHI8
Protein purity
> 90 %
Package form
liquid
Molecular weight
50 kDa
Gene number
9510
Active form?
Yes
Available target modification
No