NELF-A (negative elongation factor A), NELF-B, NELF-C, NELF-D and NELF-E are components of the NELF complex, which is a a structure that negatively regulates Pol II-dependent transcription elongation. Control of transcription elongation requires a complex interplay between positive transcription elongation factor b (P-TEFb) and negative transcription elongation factors, DSIF and NELF. DSIF and NELF, act as negative transcription elongation factors by increasing the time the polymerase spends at pause sites. DSIF/NELF inhibition of transcription is prevented by P-TEFb in cooperation with FACT.
Nasal embryonic LHRH factor; Nasal embryonic luteinizing hormone releasing hormone factor; Nasal embryonic luteinizing hormone-releasing hormone factor; Nelf; NELF_HUMAN.
If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NELF
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
This is a highly specific antibody against NELF.
This antibody was purified via Protein A.
NELF Primary Polyclonal Antibody
WB, IHC-P, IF(IHC-P)
Human, Mouse, Rat
1ug per 1ul