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Size

436

Price

2766.00

Catalog

RPC743Hu01

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Description

Hormone releasing factors and releasing hormones are  signaling molecules produced by glands in multicellular organisms. The glands that secrete Luteinizing hormones LHRG and LH, FSH comprise the endocrine signaling system. The term growth hormone releasing hormone GHRH is sometimes extended to include chemicals produced by cells that affect the same cell (autocrine or intracrine signaling) or nearby cells (paracrine signaling). Human recombinant LHRG and GHRH are produced in E. coli or in yeast cells.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

Buffer Formulation

20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.

Alternative Names

PTH1R; Parathyroid hormone/parathyroid hormone-related peptide receptor; PTH/PTHrP type I receptor

Application

Positive Control; Immunogen; SDS-PAGE; WB.

Item Name

Parathyroid Hormone Receptor 1

Additional source

Recombinants or rec. proteins

Source

Prokaryotic expression

Expression System

Prokaryotic expression

Organism species

Homo sapiens (Human)

Traits

Freeze-dried powder

Tag

N-terminal His-Tag

Research Area

Endocrinology;

Group

recombinants

Protein length

Ala28~Gly188

Purity

≥ 98%

Predicted Molecular Mass(KD)

22.2kDa

Accurate Molecular Mass(KD)

22kDa

Isoelectric Point

6.6

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