Th1 Response

F V S S H R Y V E T M L V A D Q S M A E F H G S G L K H Y L L T L F S V A A R L Y K H P S I R N S V S L V V V K I L V I H D E Q K G P E V T S N A A L T L R N F C N W Q K Q H N P P S D R D A E H Y D T A I L F T R Q D L C G S Q T C D T L G M A D V G T V C D P S R S C S V I E D D G L Q A A F T T A H E L G H V F N M P H D D A K Q C A S L N G V N Q D S H M M A S M L S N L D H S Q P W S P C S A Y M I T S F L D N G H G E C L M D K P H N P I Q L P G D L P G T S Y D A N R Q C Q F T F G E D S K H C P D A A S T C S T L W C T G T S G G V L V C Q T K H F P W A D G T S C G E G K W C I N G K C V N K T D R K H F D T P F H G N W G M W G P W G D C S R T C G G G V Q Y T M R E C D N P V P K N G G K Y C E G K R V R Y R S C N L E D C P D N (H)6

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

ADAMTS1 cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover (By similarity). Has angiogenic inhibitor activity. Active metalloprotease, which may be associated with various inflammatory processes as well as development of cancer cachexia. May play a critical role in follicular rupture.

Diseases associated with ADAMTS1 include Type 2A Von Willebrand Disease and Mongolian Spot. Among its related pathways are Diseases associated with O-glycosylation of proteins and Transport to the Golgi and subsequent modification.

A Disintegrin-Like And Metalloprotease (Reprolysin Type) With Thrombospondin Type 1 Motif, 1; Human Metalloproteinase With Thrombospondin Type 1 Motifs

Degradation of extracellular matrix proteoglycans; screening and characterization of inhibitors; Standard in enzymatic and immunological assays

Recombinant human ADAMTS1 Δ618-968 is produced with the baculovirus expression system and purified from insect cell culture supernatants.

ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family.

50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 5 mM CaCl2, 0.05 % Brij-35 Detergent.

ADAM metallopeptidase with thrombospondin type 1 motif 1 (partial)

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Recombinants or rec. proteins

Mentioned in the data sheet

For Research Use only.

See the data sheet

ADAMTS1 (partial)

protein fragment

Store at -70°C

EC 3.4.24.83

recombinants

Recombinant

Insect Cell

His-tagged

histidine

dry ice

Q9UHI8

> 90 %

liquid

50 kDa

9510

Yes

No