Th1 Response

Parathyroid hormone/parathyroid hormone-related peptide receptor, also known as PTHR, is a protein that in humans is encoded by the PTH1R gene. PTHR is a member of a family of G protein-coupled receptors. PTHR gene was mapped to the vicinity of the 3p21.3-p21.2 boundary by PCR analysis of human/rodent somatic cell hybrid panels using oligonucleotide primers designed to amplify a portion of the gene from genomic DNA. This is a receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. PTH1R functions as a receptor for parathyroid hormone and for parathyroid hormone-related protein.

After reconstitution, the PTH1R antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.

Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.

An amino acid sequence from the C-terminus of human Parathyroid Hormone Receptor 1 (KLRETNAGRCDTRQQYRKL) was used as the immunogen for this PTH1R antibody (100% homologous in human, mouse and rat).

The stated application concentrations are suggested starting amounts. Titration of the PTH1R antibody may be required due to differences in protocols and secondary/substrate sensitivity.

If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

This PTH1R antibodyis to be used only for research purposes and not for diagnostics..

Western blot: 0.5-1ug/ml,IHC (Paraffin): 0.5-1ug/ml,Immunocytochemistry: 0.5-1ug/ml

0.5mg/ml if reconstituted with 0.2ml sterile DI water

Rabbit (Oryctolagus cuniculus)

Polyclonal (rabbit origin)

Antigen affinity purified

Polyclonal antibody

Antigen affinity

WB, IHC-P, ICC

Unconjugated

anticorps

Antibody

Q03431

PTH1R