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Back to: Our Providers / bio logo / Mouse Monoclonal IgG1 Anti-Parathyroid Hormone (PTH) [A1-70]

Size

1 ml

Price

239.00

Catalog

PT101

Quick and safe buy process

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Hormone releasing factors and releasing hormones are  signaling molecules produced by glands in multicellular organisms. The glands that secrete Luteinizing hormones LHRG and LH, FSH comprise the endocrine signaling system. The term growth hormone releasing hormone GHRH is sometimes extended to include chemicals produced by cells that affect the same cell (autocrine or intracrine signaling) or nearby cells (paracrine signaling). Human recombinant LHRG and GHRH are produced in E. coli or in yeast cells.

Test

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.

Tips

*Gentaur's antibodies are intended for in vitro research use only. They must not be used for clinical diagnostics and not for in vivo experiments in humans or animals. ** The preservative sodium azide is known to be poisonous and potentially hazardous to health. It should be handled only by trained staff. Despite of the product's low azide concentration it must be handled with care. Dispose according to regional rules!

Litterature

1. Armitage E.K. (1986) Parathyrin (parathyroid hormone) metabolism and methods for assay. Clin. Chem. 32; 418ff. 2. Brown R.C., Aston J.P., Weeks I., and Woodhead J.S. (1987) Circulating intact parathyroid hormone measured by a two-site immunochemiluminometric assay. J. Clin. Endocrinol. Metab. 65; 407-414.

About

Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.

Product presentation

Antibody solution in stabilizing phosphate buffer pH 7.3. Contains 0.09 % sodium azide** and BSA. The volume is sufficient for at least 40-100 immunohistochemical tests (100 µl working solution / test). Use appropriate antibody diluent e.g. Gentaur Art .No. PU002.

Recommended secondary reagent

We recommend the use of Gentaur's Universal Staining System DAB (Art. No. DA005) or AEC (Art.-No. AE005), if higher sensitivity is required VECTASTAIN Elite ABC (Art. No. PK-6102), ABC AP (Art. No. AK-5002) or VECTOR ImmPress Mouse IgG systems are applicable.

Specificity

Human Parathyroid Hormone N-terminal (1-38) and (1-34), detected epitope PTH (15-25), no cross-reactivity with PTH (44-68) and PTH (53-84)

Pretreatment

Pre-treatment with unmasking fluid G (Art. No. DE007) or C (Art. No. DE000) at 90-100°C is recommended!

Availability

Please contact us to check the availability

Immunogen

Synthetic human parathyroid hormone (1-38)

UniProt number

Go to UniProt/SwissProt

Product is supplied as

liquid concentrate

Positive control

Parathyroid Gland

Product category

Primary Antibody

Storage method

Store at 2-8°C

Latin name

Mus musculus

Recommended concentration for use

1:4 - 1:10

Tested applications

IHC(C, P)

Protein concentration

20 µg/ml

Antibody's clone

A1-70

Antibody's raised in

Mouse

Species reactivity

Human

Antibody's isotype

IgG1

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