SMARCA2 is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Two transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism.
SMARCA2 antibody can be used for detection of SMARCA2 by ELISA at 1:312500. SMARCA2 antibody can be used for detection of SMARCA2 by western blot at 0.5 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
For short periods of storage (days) store at 4 grades C. For longer periods of storage, store SMARCA2 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SMARCA2.
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SMARCA2, BRM, SNF2, SWI2, hBRM, NCBRS, Sth1p, BAF190, SNF2L2, SNF2LA, hSNF2a
Antibody is purified by peptide affinity chromatography method.
ELISA, Western Blot, immuno-histo-chemistry
Human, Mouse, Rat, Dog, Zebrafish