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Size
436
Price
2766.00
Catalog
RPC743Hu01
Quick and safe buy process
Description
Hormone releasing factors and releasing hormones are signaling molecules produced by glands in multicellular organisms. The glands that secrete Luteinizing hormones LHRG and LH, FSH comprise the endocrine signaling system. The term growth hormone releasing hormone GHRH is sometimes extended to include chemicals produced by cells that affect the same cell (autocrine or intracrine signaling) or nearby cells (paracrine signaling). Human recombinant LHRG and GHRH are produced in E. coli or in yeast cells.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
Buffer Formulation
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Alternative Names
PTH1R; Parathyroid hormone/parathyroid hormone-related peptide receptor; PTH/PTHrP type I receptor
Application
Positive Control; Immunogen; SDS-PAGE; WB.
Item Name
Parathyroid Hormone Receptor 1
Additional source
Recombinants or rec. proteins
Source
Prokaryotic expression
Expression System
Prokaryotic expression
Organism species
Homo sapiens (Human)
Traits
Freeze-dried powder
Tag
N-terminal His-Tag
Research Area
Endocrinology;
Group
recombinants
Protein length
Ala28~Gly188
Purity
≥ 98%
Predicted Molecular Mass(KD)
22.2kDa
Accurate Molecular Mass(KD)
22kDa
Isoelectric Point
6.6