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Size

500ul

Price

652.00

Catalog

GEN607553

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Description

Hormone releasing factors and releasing hormones are  signaling molecules produced by glands in multicellular organisms. The glands that secrete Luteinizing hormones LHRG and LH, FSH comprise the endocrine signaling system. The term growth hormone releasing hormone GHRH is sometimes extended to include chemicals produced by cells that affect the same cell (autocrine or intracrine signaling) or nearby cells (paracrine signaling). Human recombinant LHRG and GHRH are produced in E. coli or in yeast cells.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

Other names

parathyroid hormone/parathyroid hormone-related peptide receptor; Parathyroid hormone/parathyroid hormone-related peptide receptor; parathyroid hormone/parathyroid hormone-related peptide receptor; PTH1 receptor; PTH/PTHr receptor; PTH/PTHrP type I receptor; parathyroid hormone receptor 1; seven transmembrane helix receptor; parathyroid hormone/parathyroid hormone-related protein receptor; parathyroid hormone 1 receptor; PTH/PTHrP type I receptor; PTH/PTHr receptor; Parathyroid hormone 1 receptor

Storage and shipping

Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze atStore the antibody at -20 degrees Celsius. or colder. Aliquots are stable for at least 12 months atStore the antibody at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Specificity and cross-reactivity

Recognizes Parathyroid Hormone Receptor Type I. Does not react with Parathyroid Hormone Receptor Type II. Species Crossreactivity: Human.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

Species reactivity

Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

Form/Appearance

Supplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.09% sodium azide. Also available without BSA and azide. See P3109-51X.

Gene name

PTH1R; PTH1R; PFE; PTHR; PTHR1; PTHR; PTHR1; PTH/PTHr receptor

Gene name synonims

PTH1R; PTH1R; PFE; PTHR; PTHR1; PTHR; PTHR1; PTH/PTHr receptor

Other gene names

PTH1R; PTH1R; PFE; PTHR; PTHR1; PTHR; PTHR1; PTH/PTHr receptor

Purification method

Affinity Purified by Protein G affinity chromatography.

Tested applications:

Western Blot (WB), Immunohistochemistry (IHC)

Also known as

Parathyroid Hormone Receptor Type 1

Source organism

Human (Homo sapiens)

Subcategory

Mnoclonal antibodies

Host organism

Mouse (Mus musculus)

Clonality

Monoclonal

Category

Antibodies

Immunoglobulin isotype

IgG1,k

Clone

3F311

Concentration

N/A

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