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Back to: Our Providers / Cusabio / Rabbit Anti Human,Mouse NTHL1 Antibody-Non-conjugated
Size
50ug
Price
212.00
Catalog
CSB-PA016125LA01HU_50ug
Quick and safe buy process
Background
Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. Has also 8-oxo-7,8-dihydroguanine (8-oxoG) DNA glycosylase activity. Acts preferentially on DNA damage opposite guanine residues in DNA. Is able to process lesions in nucleosomes without requiring or inducing nucleosome disruption.
Properties
If you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
About
Rabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
Shipping and storage
NTHL1 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
Alias
Endonuclease III-like protein 1,Bifunctional DNA N-glycosylase/DNA-(apurinic or apyrimidinic site) lyase,NTHL1
Buffer composition
Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Immunogen type
Recombinant Human Endonuclease III-like protein 1 protein (31-312AA)
Tested applications & recommended dilutions
ELISA,WB,IF;Recommended dilution:WB:1:500-1:5000,IF:1:50-1:200
Long name
Rabbit Antibody against Human, Mouse NTHL1, Non-conjugated
Latin name
Mus musculus,Oryctolagus cuniculus
Short name of the antigen
Endonuclease III-like protein 1
Synonym name
NTHL1 Human, Mouse Antibody
Format
Liquid, diluted in buffer
Antibody category
Polyclonal Antibodies
Clonality
Polyclonal antibody
Purification method
Protein G purified
Conjugation
Non-conjugated
Species reactivity
Human,Mouse
French translation
anticorps
UniProt ID
P78549
Immunogen species
Human
Purity
>95%
Antibody isotype
IgG